The University of Twente is a public technical university located in Enschede, the Netherlands. The university was founded in 1961 as Technische Hogeschool Twente or (THT). The University of Twente was built on the former country estate of Drienerlo, situated between Hengelo and Enschede. The 140-hectare estate consists of woodland, meadows and water. Architects Van Tijen and Van Embden designed the first — and so far only — Dutch campus university along American lines where students and staff live, work and pursue their leisure activities on campus.

The degree programs at the University of Twente range from business administration and psychology to applied physics, engineering and biomedical technology.

In the applied sciences, the emphasis is on nanotechnology, process technology, engineering, information and communication technology, and the biomedical sciences.

So far, the UT has produced over 1,000 spin-off companies; more than any other Dutch university.[10] UT is also one of the founders of Novel-T, formerly Stichting Kennispark Twente, a startup accelerator and support program for university spin-offs.